Niss may have less hp and con but look where it goes. Niss (well atleast mine) put points on int, wis and agi, in that order. So she may not stand long in a battle but she can pack a punch. So in terms of a Niss and a Fred doing 1 hit against the shiba inu in Kelan I would say Niss wins. But if you put her in a quest she'll fly faster than you can blink. So in the long run Fred will do more damage because he can stay alive longer in battles to deal out more damage.